Article
CD11b(+) Mononuclear Cells Mitigate Hyperoxia-Induced Lung Injury in Neonatal Mice.
American journal of respiratory cell and molecular biology - 1 Feb 2016
Eldredge Laurie C, Treuting Piper M, Manicone Anne M, Ziegler Steven F, Parks William C, McGuire John K
Abstract excerpt
Bronchopulmonary dysplasia (BPD) is a common consequence of life-saving interventions for infants born with immature lungs. Resident tissue myeloid cells regulate lung pathology, but their role in BPD is poorly understood. To determine the role of lung interstitial myeloid cells in neonatal responses to lung injury, we exposed newborn mice to hyperoxia, a neonatal mouse lung injury model with features of human...
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