Article
Resident alveolar macrophages are master regulators of arrested alveolarization in experimental bronchopulmonary dysplasia.
The Journal of pathology - 1 Jun 2018
Kalymbetova Tatiana V, Selvakumar Balachandar, Rodríguez-Castillo José Alberto, Gunjak Miša, Malainou Christina, Heindl Miriam Ruth, Moiseenko Alena, Chao Cho-Ming, Vadász István, Mayer Konstantin, Lohmeyer Jürgen, Bellusci Saverio, Böttcher-Friebertshäuser Eva, Seeger Werner, Herold Susanne, Morty Rory E
Abstract excerpt
Trophic functions for macrophages are emerging as key mediators of developmental processes, including bone, vessel, and mammary gland development. Yolk sac-derived macrophages mature in the distal lung shortly after birth. Myeloid-lineage macrophages are recruited to the lung and are activated under pathological conditions. These pathological conditions include bronchopulmonary dysplasia (BPD), a common...
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