Article
Thyroid hormone transporters in health and disease: advances in thyroid hormone deiodination.
Best practice & research. Clinical endocrinology & metabolism - 1 Jun 2007
Köhrle Josef
Abstract excerpt
Thyroid hormone metabolism by the three deiodinase selenoproteins -- DIO1, DIO2, and DIO3 -- regulates the local availability of various iodothyronine metabolites and thus mediates their effects on gene expression, thermoregulation, energy metabolism, and many key reactions during the development and maintenance of an adult organism. Circulating serum levels of thyroid hormone and thyroid-stimulating hormone,...
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