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Article

Genetics in endocrinology: genetic variation in deiodinases: a systematic review of potential clinical effects in humans.

European journal of endocrinology - 1 Sept 2014

Verloop Herman, Dekkers Olaf M, Peeters Robin P, Schoones Jan W, Smit Johannes W A

Abstract excerpt

Iodothyronine deiodinases represent a family of selenoproteins involved in peripheral and local homeostasis of thyroid hormone action. Deiodinases are expressed in multiple organs and thyroid hormone affects numerous biological systems, thus genetic variation in deiodinases may affect multiple clinical endpoints. Interest in clinical effects of genetic variation in deiodinases has clearly increased. We aimed to...

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Identifiers

PMID: 24878678
DOI: 10.1530/EJE-14-0302

Genes

IGF1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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