Article
ADIPOQ -11377C>G Polymorphism Increases the Risk of Adipokine Abnormalities and Child Obesity Regardless of Dietary Intake.
Journal of pediatric gastroenterology and nutrition - 1 Jan 2016
Gajewska Joanna, Kuryłowicz Alina, Ambroszkiewicz Jadwiga, Mierzejewska Ewa, Chełchowska Magdalena, Szamotulska Katarzyna, Weker Halina, Puzianowska-Kuźnicka Monika
Abstract excerpt
OBJECTIVE: The aim of the present study was to verify whether selected functional single nucleotide polymorphisms in LEP, LEPR, and ADIPOQ loci are associated with the development of obesity and serum levels of the respective adipokines in prepubertal white children with obesity. METHODS: Frequencies of -2548G>A LEP (rs7799039), Q223R (rs1137101) and K656N (rs8129183) LEPR, and -11377C>G (rs266729) and -11426A>G...
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