Article
Early detrimental metabolic outcomes of rs17300539-A allele of ADIPOQ gene despite higher adiponectinemia.
Obesity (Silver Spring, Md.) - 1 Jul 2010
Morandi Anita, Maffeis Claudio, Lobbens Stéphane, Bouatia-Naji Nabila, Heude Barbara, Pinelli Leonardo, Meyre David, Froguel Philippe
Abstract excerpt
Minor allele A of single-nucleotide polymorphism (SNP) 11391 G/A of ADIPOQ gene (rs17300539) has been consistently associated with higher adiponectin levels in adults and children. The aim of this study was to investigate the metabolic role of this variant in a large cohort of children of European origin. A total of 1,852 children from two general populations in Verona and in Fleurbaix-Laventie and from the Lille...
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