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Article

Associations of MC4R, LEP, and LEPR Polymorphisms with Obesity-Related Parameters in Childhood and Adulthood.

Genes - 21 Jun 2021

Raskiliene Asta, Smalinskiene Alina, Kriaucioniene Vilma, Lesauskaite Vaiva, Petkeviciene Janina

Abstract excerpt

MC4R, LEP, and LEPR genes are involved in the hypothalamic leptin-melanocortin regulation pathway, which is important for energy homeostasis. Our study aimed to evaluate the associations between the MC4R rs17782313, LEP rs7799039, and LEPR rs1137101 polymorphisms with obesity-related parameters in childhood and adulthood. The data were obtained from the Kaunas Cardiovascular Risk Cohort study, which started in...

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Source

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Identifiers

PMID: 34205732
DOI: 10.3390/genes12060949
PMCID: PMC8235002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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