Article
Association of LEP rs7799039 and LEPR rs1137101 polymorphisms with obesity in Vietnamese preschool children.
Pediatrics and neonatology - 1 Nov 2025
Le Thi Tuyet, Pham Bui Quang Minh, Nguyen Thi Trung Thu, Nguyen Thi Hong Hanh, Le Thi Thuy Dung
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) in genes that regulate body weight and energy homeostasis, such as LEP and LEPR, may influence susceptibility to obesity. The present study aims to evaluate the association of LEP rs7799039 and LEPR rs1137101 polymorphisms with obesity in Vietnamese preschool children. METHODS: A case-control study was conducted on 1146 preschool children aged 3-6 years (360...
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