Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of three common SNPs in 5'-flanking region of LEP and ADIPOQ genes on their expression in Polish obese children and adolescents.

Molecular biology reports - 1 Apr 2012

Cieslak J, Bartz M, Stachowiak M, Skowronska B, Majewska K A, Harasymczuk J, Stankiewicz W, Fichna P, Switonski M

Abstract excerpt

Genes encoding adipokines are considered as candidates for human obesity. In this study we analyzed the expression of leptin (LEP) and adiponectin (ADIPOQ) genes in relation to common 5'-flanking or 5'UTR variants: -2548G>A (LEP), 19A>G (LEP) and -11377C>G (ADIPOQ) in Polish obese children and adolescents. Relative transcription levels in the subcutaneous adipose tissue (real time RT-PCR) and serum protein...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5' Flanking Region
Share to Adiponectin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Genes, Dominant

Share to Genes, Recessive

Share to Leptin

Share to Obesity

Share to Poland

Source

Open in PubMed Open full text

Identifiers

PMID: 21755292
DOI: 10.1007/s11033-011-1174-7
PMCID: PMC3294210

Genes

LEP
ADIPOQ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of three common SNPs in 5'-flanking region of LEP and ADIPOQ genes on their expression in Polish obese children and adolescents.PMID 21755292Read ↗

Polymorphisms in 5'-flanking regions of genes encoding adiponectin, leptin, and resistin are not associated with obesity of Polish children and adolescents.Semantic proximity Read ↗

ADIPOQ -11377C>G Polymorphism Increases the Risk of Adipokine Abnormalities and Child Obesity Regardless of Dietary Intake.Semantic proximity Read ↗

Genetics of leptin and obesity: a HuGE review.Semantic proximity Read ↗

Genetic polymorphisms in adipokine genes and the risk of obesity: a systematic review and meta-analysis.Semantic proximity Read ↗

Adipokine Gene Single-Nucleotide Polymorphisms in Portuguese Obese Adolescents: Associations with Plasma Concentrations of Adiponectin, Resistin, IL-6, IL-1β, and TNF-α.Semantic proximity Read ↗

Leptin G-2548A and leptin receptor Q223R gene polymorphisms are not associated with obesity in Romanian subjects.Semantic proximity Read ↗

Association of the G-2548A polymorphism in the 5' region of the LEP gene with overweight.Semantic proximity Read ↗

LEP -2548G>A Polymorphism of the Leptin Gene and Its Influence on the Lipid Profile in Obese Individuals.Semantic proximity Read ↗

Influence of the leptin G-2548A polymorphism on leptin levels and anthropometric measurements in healthy Spanish adolescents.Semantic proximity Read ↗

Lack of mutations in the leptin receptor gene in severely obese children.Semantic proximity Read ↗

GHRL, LEP, LEPR genes polymorphism and their association with the metabolic syndrome in the Ukrainian population.Semantic proximity Read ↗

Correlations Between Leptin Gene Polymorphisms 223 A/G, 1019 G/A, 492 G/C, 976 C/A, and Anthropometrical and Biochemical Parameters in Children With Obesity: A Prospective Case-Control Study in a Romanian Population-The Nutrichild Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.