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Article

Association between LEPR, FTO, MC4R, and PPARG-2 polymorphisms with obesity traits and metabolic phenotypes in school-aged children.

Endocrine - 1 Jun 2018

Almeida Sílvia M, Furtado José M, Mascarenhas Paulo, Ferraz Maria E, Ferreira José C, Monteiro Mariana P, Vilanova Manuel, Ferraz Fernando P

Abstract excerpt

PURPOSE: Evaluate the relationship of leptin receptor (LEPR) rs1137101, fat mass obesity-associated (FTO) receptors 9939609, melanocortin-4 receptors (MC4R) rs2229616 and rs17782313, and proliferator-activated receptor-gamma (PPARG) rs1801282 with clinical and metabolic phenotypes in prepubertal children. RESEARCH QUESTION: What is the effect of polymorphisms on clinical and metabolic phenotypes in prepubertal...

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Topics

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Share to Adiposity
Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO
Share to Body Mass Index
Share to Body Weight
Share to PPAR gamma
Share to Receptor, Melanocortin, Type 4
Share to Receptors, Leptin
Share to Waist Circumference

Source

Open in PubMed Open full text

Identifiers

PMID: 29679223
DOI: 10.1007/s12020-018-1587-3
PMCID: PMC5937906

Genes

FTO
LEPR
PPARG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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