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Article

IGF2, LEPR, POMC, PPARG, and PPARGC1 gene variants are associated with obesity-related risk phenotypes in Brazilian children and adolescents.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Jul 2015

Queiroz E M, Cândido A P C, Castro I M, Bastos A Q A, Machado-Coelho G L L, Freitas R N

Abstract excerpt

Association studies of genetic variants and obesity and/or obesity-related risk factors have yielded contradictory results. The aim of the present study was to determine the possible association of five single-nucleotide polymorphisms (SNPs) located in the IGF2, LEPR, POMC, PPARG, and PPARGC1 genes with obesity or obesity-related risk phenotypes. This case-control study assessed overweight (n=192) and...

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Anthropometry
Cardiovascular Diseases
Cholesterol
Insulin-Like Growth Factor II
Overweight

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pro-Opiomelanocortin

Receptors, Leptin

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Open in PubMed Open full text

Identifiers

PMID: 25923461
DOI: 10.1590/1414-431X20154155
PMCID: PMC4512097

Genes

LEPR
IGF2
POMC
PPARG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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