Article
Complementary Effects of Genetic Variations in LEPR on Body Composition and Soluble Leptin Receptor Concentration after 3-Month Lifestyle Intervention in Prepubertal Obese Children.
Nutrients - 27 May 2016
Gajewska Joanna, Kuryłowicz Alina, Mierzejewska Ewa, Ambroszkiewicz Jadwiga, Chełchowska Magdalena, Weker Halina, Puzianowska-Kuźnicka Monika
Abstract excerpt
In obese individuals, weight loss might be affected by variants of the adipokine-encoding genes. We verified whether selected functional single nucleotide polymorphisms in LEP, LEPR and ADIPOQ are associated with changes in serum levels of the respective adipokines and weight loss in 100 prepubertal obese (SDS-BMI > 2) Caucasian children undergoing lifestyle intervention. Frequencies of the -2548G > A LEP, Q223R...
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