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Article

Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells.

Blood - 10 May 2012

Duhen Thomas, Duhen Rebekka, Lanzavecchia Antonio, Sallusto Federica, Campbell Daniel J

Abstract excerpt

FOXP3+ regulatory T (Treg) cells are a broadly acting and potent anti-inflammatory population of CD4+ T cells essential for maintaining immune homeostasis and preventing debilitating autoimmunity. Based on chemokine receptor expression, we identified distinct populations of Treg cells in human blood expected to colocalize with different Th cell subsets. Although each population was functionally suppressive, they...

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Source

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Identifiers

PMID: 22438251
DOI: 10.1182/blood-2011-11-392324
PMCID: PMC3362361

Genes

FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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