Article
The European GWAS-identified risk SNP rs457717 within IQGAP2 is not associated with age-related hearing impairment in Han male Chinese population.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery - 1 Jul 2016
Luo Huajie, Wu Hao, Shen Hailian, Chen Haifeng, Yang Tao, Huang Zhiwu, Jin Xiaojie, Pang Xiuhong, Li Lei, Hu Xianting, Jiang Xuemei, Fan Zhuping, Li Jiping
Abstract excerpt
This study aimed to test the association between the European GWAS-identified risk IQGAP2 SNP rs457717 (A>G) and age-related hearing impairment (ARHI) in a Han male Chinese (HMC) population. A total of 2420 HMC subjects were divided into two groups [group 70+: >70 years (n = 1306), and group 70-: ≤70 years (n = 1114)]. The participants were categorised into case and control groups according to Z high scores for...
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