Article
A genome-wide association study for age-related hearing impairment in the Saami.
European journal of human genetics : EJHG - 1 Jun 2010
Van Laer Lut, Huyghe Jeroen R, Hannula Samuli, Van Eyken Els, Stephan Dietrich A, Mäki-Torkko Elina, Aikio Pekka, Fransen Erik, Lysholm-Bernacchi Alana, Sorri Martti, Huentelman Matthew J, Van Camp Guy
Abstract excerpt
This study aimed at contributing to the elucidation of the genetic basis of age-related hearing impairment (ARHI), a common multifactorial disease with an important genetic contribution as demonstrated by heritability studies. We conducted a genome-wide association study (GWAS) in the Finnish Saami, a small, ancient, genetically isolated population without evidence of demographic expansion. The choice of this...
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