Article
Association of cadherin23 single nucleotide polymorphism with age-related hearing impairment in Han Chinese.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery - 1 Sept 2012
Hwang Juen-Haur, Liu Kris Sun, Wu Chien-Chi, Liu Tien-Chen
Abstract excerpt
OBJECTIVE: Genetic variation of cadheri23 (cdh23; 753G>A in exon 7) has been implicated with age-related hearing impairment (ARHI) in mice. This study aimed to test the association of the CDH23 tag single nucleotide polymorphism (SNP) in intron 7 with ARHI in Han Chinese. STUDY DESIGN: Individual cohort study. SETTING: Tertiary medical center. SUBJECTS AND METHODS: A total of 1175 Han Chinese subjects were...
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