Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

A Genome-Wide Association Study of Age-Related Hearing Impairment in Middle- and Old-Aged Chinese Twins.

BioMed research international - 1 Jan 2021

Duan Haiping, Song Wanxue, Wang Weijing, Cao Hainan, Wang Bingling, Liu Yan, Xu Chunsheng, Wu Yili, Pang Zengchang, Zhang Dongfeng

Abstract excerpt

BACKGROUND: Age-related hearing impairment (ARHI) is considered an unpreventable disorder. We aimed to detect specific genetic variants that are potentially related to ARHI via genome-wide association study (GWAS). METHODS: A sample of 131 dizygotic twins was genotyped for single-nucleotide polymorphism- (SNP-) based GWAS. Gene-based test was performed using VEGAS2. Pathway enrichment analysis was conducted by...

Topics

Aged
Aging
Asian People
China
Female
Genetic Predisposition to Disease
Genome-Wide Association Study
Humans
Male
Middle Aged
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Presbycusis

Twins, Dizygotic

Source

Open in PubMed Open full text

Identifiers

PMID: 34337005
DOI: 10.1155/2021/3629624
PMCID: PMC8314043

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Genome-Wide Association Study of Age-Related Hearing Impairment in Middle- and Old-Aged Chinese Twins.PMID 34337005Read ↗

A Large Genome-Wide Association Study of Age-Related Hearing Impairment Using Electronic Health Records.Semantic proximity Read ↗

Multi-ancestry GWAS of age-related hearing loss identifies 140 loci and key cellular mechanisms.Semantic proximity Read ↗

Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment.Semantic proximity Read ↗

Transcriptome-wide association study identifies novel susceptibility genes contributing to hearing impairmentSemantic proximity Read ↗

A Phenome-Wide Comorbidity Atlas of Age-Related Hearing Loss, Speech-in-Noise Deficits, and Tinnitus: Distinguishing Causal Signals from Correlation.Semantic proximity Read ↗

New insights into the complex genetic architecture of age-related hearing loss.Semantic proximity Read ↗

The genetic architecture of age-related hearing impairment revealed by genome-wide association analysis.Semantic proximity Read ↗

Hearing impairment: a panoply of genes and functions.Semantic proximity Read ↗

Molecular genetic epidemiology of age-related hearing impairment.Semantic proximity Read ↗

The genetic landscape of age-related hearing loss.Semantic proximity Read ↗

Genome-wide association analysis demonstrates the highly polygenic character of age-related hearing impairment.Semantic proximity Read ↗

Novel pathogenic mutations and further evidence for clinical relevance of genes and variants causing hearing impairment in Tunisian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.