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Article

A Large Genome-Wide Association Study of Age-Related Hearing Impairment Using Electronic Health Records.

PLoS genetics - 1 Oct 2016

Hoffmann Thomas J, Keats Bronya J, Yoshikawa Noriko, Schaefer Catherine, Risch Neil, Lustig Lawrence R

Abstract excerpt

Age-related hearing impairment (ARHI), one of the most common sensory disorders, can be mitigated, but not cured or eliminated. To identify genetic influences underlying ARHI, we conducted a genome-wide association study of ARHI in 6,527 cases and 45,882 controls among the non-Hispanic whites from the Genetic Epidemiology Research on Adult Health and Aging (GERA) cohort. We identified two novel genome-wide...

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Identifiers

PMID: 27764096
DOI: 10.1371/journal.pgen.1006371
PMCID: PMC5072625

Genes

SDS
EYA4
ILDR1
ISG20
TRIOBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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