Article
The grainyhead-like 2 gene (GRHL2) single nucleotide polymorphism is not associated with age-related hearing impairment in Han Chinese.
The Laryngoscope - 1 Jun 2011
Lin Yan-Han, Wu Chen-Chi, Hsu Chuan-Jen, Hwang Juen-Haur, Liu Tien-Chen
Abstract excerpt
OBJECTIVES/HYPOTHESIS: The grainyhead-like 2 gene (GRHL2) was found to be associated with age-related hearing impairment (ARHI) in Europeans. We tested whether the same association exists in the Han Chinese population. STUDY DESIGN: Individual cohort study. METHODS: Among a total of 1,175 Han Chinese volunteers, 310 were classified into the case group (the 26% with poorest hearing), and 308 were placed into the...
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