Article
Functional dissection of the Pax6 paired domain: Roles in neural tube patterning and peripheral nervous system development.
Developmental biology - 1 May 2016
Huettl Rosa-Eva, Eckstein Simone, Stahl Tessa, Petricca Stefania, Ninkovic Jovica, Götz Magdalena, Huber Andrea B
Abstract excerpt
During development of the CNS, stem and progenitor cell proliferation, cell fate designation, and patterning decisions are tightly regulated by interdependent networks of key transcriptional regulators. In a genetic approach we analyzed divergent functionality of the PAI and RED sub-domains of the Pax6 Paired domain (PD) during progenitor zone formation, motor and interneuron development, and peripheral...
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