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Article

Notch signalling regulates epibranchial placode patterning and segregation.

Development (Cambridge, England) - 17 Feb 2020

Wang Li, Xie Junjie, Zhang Haoran, Tsang Long Hin, Tsang Sze Lan, Braune Eike-Benjamin, Lendahl Urban, Sham Mai Har

Abstract excerpt

Epibranchial placodes are the geniculate, petrosal and nodose placodes that generate parts of cranial nerves VII, IX and X, respectively. How the three spatially separated placodes are derived from the common posterior placodal area is poorly understood. Here, we reveal that the broad posterior placode area is first patterned into a Vgll2+/Irx5+ rostral domain and a Sox2+/Fgf3+/Etv5+ caudal domain relative to the...

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Identifiers

PMID: 31988190
DOI: 10.1242/dev.183665
PMCID: PMC7044445

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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