Article
Specification of sense-organ identity by a Caenorhabditis elegans Pax-6 homologue.
Nature - 7 Sept 1995
Zhang Y, Emmons S W
Abstract excerpt
The Pax-6 transcription-factor gene, containing a paired domain and a paired-type homeodomain, is conserved in structure and ubiquitously present among Metazoa. It is required for development of the central nervous system, and is mutated in human aniridia, mouse and rat small eye and Drosophila e...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Caenorhabditis
- Caenorhabditis elegans Proteins
- DNA, Helminth
- DNA-Binding Proteins
- Eye Proteins
- Genes, Helminth
- Genes, Reporter
- Helminth Proteins
- Homeodomain Proteins
- Male
- Molecular Sequence Data
- Mutation
- PAX6 Transcription Factor
- Paired Box Transcription Factors
- Repressor Proteins
