Article
Loss- and gain-of-function analyses reveal targets of Pax6 in the developing mouse telencephalon.
Molecular and cellular neurosciences - 1 Jan 2007
Holm Pontus C, Mader Michael T, Haubst Nicole, Wizenmann Andrea, Sigvardsson Mikael, Götz Magdalena
Abstract excerpt
Appropriate neurogenesis and patterning of the forebrain requires the transcription factor Pax6, yet it is largely unknown how Pax6 exerts its effects at the molecular level. To characterize Pax6-mediated regulation of gene expression during murine forebrain neurogenesis, we performed microarray analysis with tissue from the dorsal Pax6-dependent telencephalon and the ventral Pax6-negative telencephalon at the...
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