Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Atherosclerosis following renal injury is ameliorated by pioglitazone and losartan via macrophage phenotype.

Atherosclerosis - 1 Sept 2015

Yamamoto Suguru, Zhong Jiayong, Yancey Patricia G, Zuo Yiqin, Linton MacRae F, Fazio Sergio, Yang Haichun, Narita Ichiei, Kon Valentina

Abstract excerpt

OBJECTIVE: Chronic kidney disease (CKD) amplifies atherosclerosis, which involves renin-angiotensin system (RAS) regulation of macrophages. RAS influences peroxisome proliferator-activated receptor-γ (PPARγ), a modulator of atherogenic functions of macrophages, however, little is known about its effects in CKD. We examined the impact of combined therapy with a PPARγ agonist and angiotensin receptor blocker on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensin Receptor Antagonists
Share to Aortic Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyperlipidemias

Share to Losartan

Share to Nephrectomy

Share to Pioglitazone

Share to Renin-Angiotensin System

Share to Thiazolidinediones

Source

Open in PubMed Open full text

Identifiers

PMID: 26184694
DOI: 10.1016/j.atherosclerosis.2015.06.055
PMCID: PMC4850906

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Atherosclerosis following renal injury is ameliorated by pioglitazone and losartan via macrophage phenotype.PMID 26184694Read ↗

Macrophage polarization by angiotensin II-type 1 receptor aggravates renal injury-acceleration of atherosclerosis.Semantic proximity Read ↗

Macrophage polarization in innate immune responses contributing to pathogenesis of chronic kidney diseaseSemantic proximity Read ↗

Macrophage Ontogeny, Phenotype, and Function in Ischemia Reperfusion-Induced Injury and Repair.Semantic proximity Read ↗

Macrophages in renal disease.Semantic proximity Read ↗

Understanding the role of alternative macrophage phenotypes in human atherosclerosis.Semantic proximity Read ↗

Macrophages polarization in renal inflammation and fibrosis animal models (Review)Semantic proximity Read ↗

Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis.Semantic proximity Read ↗

Phenotypic Characterization of Macrophages from Rat Kidney by Flow Cytometry.Semantic proximity Read ↗

The myeloid mineralocorticoid receptor controls inflammatory and fibrotic responses after renal injury via macrophage interleukin-4 receptor signaling.Semantic proximity Read ↗

M1- and M2-Type Macrophage Responses Are Predictive of Adverse Outcomes in Human AtherosclerosisSemantic proximity Read ↗

The role of macrophages in fibrosis of chronic kidney disease.Semantic proximity Read ↗

Distinct macrophage phenotypes contribute to kidney injury and repair.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.