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The role of macrophages in fibrosis of chronic kidney disease.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Aug 2024

Li Guangtao, Yang Hongxia, Zhang Dan, Zhang Yanghe, Liu Bin, Wang Yuxiong, Zhou Honglan, Xu Zhi-Xiang, Wang Yishu

Abstract excerpt

Macrophages are widely distributed throughout various tissues of the body, and mounting evidence suggests their involvement in regulating the tissue microenvironment, thereby influencing disease onset and progression through direct or indirect actions. In chronic kidney disease (CKD), disturbances in renal functional homeostasis lead to inflammatory cell infiltration, tubular expansion, glomerular atrophy, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38968801
DOI: 10.1016/j.biopha.2024.117079

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