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Article

M1- and M2-Type Macrophage Responses Are Predictive of Adverse Outcomes in Human Atherosclerosis

19 Jul 2016

Abstract excerpt

Atherosclerosis is an inflammatory disease caused by endothelial injury, lipid deposition, and oxidative stress. This progressive disease can be converted into an acute clinical event by plaque rupture and thrombosis. In the context of atherosclerosis, the underlying cause of myocardial infarction and stroke, macrophages uniquely possess a dual functionality, regulating lipid accumulation and metabolism and...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 27486460
DOI: 10.3389/fimmu.2016.00275

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