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Article

Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis.

Proceedings of the National Academy of Sciences of the United States of America - 18 Apr 2006

Mulligan Megan K, Ponomarev Igor, Hitzemann Robert J, Belknap John K, Tabakoff Boris, Harris R Adron, Crabbe John C, Blednov Yuri A, Grahame Nicholas J, Phillips Tamara J, Finn Deborah A, Hoffman Paula L, Iyer Vishwanath R, Koob George F, Bergeson Susan E

Abstract excerpt

Much evidence from studies in humans and animals supports the hypothesis that alcohol addiction is a complex disease with both hereditary and environmental influences. Molecular determinants of excessive alcohol consumption are difficult to study in humans. However, several rodent models show a high or low degree of alcohol preference, which provides a unique opportunity to approach the molecular complexities...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16618939
DOI: 10.1073/pnas.0510188103
PMCID: PMC1458884

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