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Article

Inflammasome polymorphisms in juvenile systemic lupus erythematosus.

Autoimmunity - 1 Jan 2015

Pontillo Alessandra, Reis Edione C, Liphaus Bernadete L, Silva Clovis A, Carneiro-Sampaio Magda

Abstract excerpt

Inflammasome is the cytoplasmic complex responsible for pro-IL1 β cleavage and secretion of IL-1β. Recently our group reported the first association between polymorphisms in the inflammasome receptor NLRP1 and adult-onset systemic lupus erythematosus (SLE) "di per se" and especially in SLE-associated renal disease, suggesting the involvement of NLRP1-inflammasome in the immune dysregulation characteristic of SLE...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26182076
DOI: 10.3109/08916934.2015.1064399

Genes

NLRP1
CARD8
NLRP3
TNFAIP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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