Article
PDCD1 single nucleotide genes polymorphisms confer susceptibility to juvenile-onset systemic lupus erythematosus.
Autoimmunity - 1 Jan 2015
Mahmoudi Mahdi, Rezaiemanesh Alireza, Salmaninejad Arash, Harsini Sara, Poursani Shiva, Bahrami Tayyeb, Tahghighi Fatemeh, Ziaee Vahid, Rezaei Nima
Abstract excerpt
Juvenile-onset systemic lupus erythematosus (JSLE) is a multisystem autoimmune disease in which both the genetic and environmental factors seem to be involved in the etiopathogenesis of the disease. The aim of this study was to evaluate the association of programmed cell death 1 (PDCD1, also called PD-1) gene polymorphisms with JSLE susceptibility in Iranian population. In this case-control association study,...
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