Article
Tumor necrosis factor-alpha single nucleotide polymorphisms in juvenile systemic lupus erythematosus.
Human immunology - 1 Aug 2015
Tahghighi Fatemeh, Ziaee Vahid, Moradinejad Mohammad Hassan, Rezaei Arezou, Harsini Sara, Soltani Samaneh, Sadr Maryam, Mahmoudi Maryam, Aghighi Yahya, Rezaei Nima
Abstract excerpt
BACKGROUND: Juvenile systemic lupus erythematosus (JSLE) is a multi-system autoimmune disorder of unknown origin. Given the importance of the contribution of pro-inflammatory cytokines, including tumor necrosis factor-alpha (TNF-α), towards the pathogenesis of JSLE, this study was performed to assess TNFA gene polymorphisms in a case-control study. METHODS: Fifty nine patients with JSLE were enrolled in this...
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