Article
STX11 functions as a novel tumor suppressor gene in peripheral T-cell lymphomas.
Cancer science - 1 Oct 2015
Yoshida Noriaki, Tsuzuki Shinobu, Karube Kennosuke, Takahara Taishi, Suguro Miyuki, Miyoshi Hiroaki, Nishikori Momoko, Shimoyama Masanori, Tsukasaki Kunihiro, Ohshima Koichi, Seto Masao
Abstract excerpt
Peripheral T-cell lymphomas (PTCL) are a heterogeneous group of non-Hodgkin lymphomas with poor prognosis. Their molecular pathogenesis has not been entirely elucidated. We previously showed that 6q24 is one of the most frequently deleted regions in primary thyroid T-cell lymphoma. In this study, we extended the analysis to other subtypes of PTCL and performed functional assays to identify the causative genes of...
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