Article
Extensive analysis of D7S486 in primary gastric cancer supports TESTIN as a candidate tumor suppressor gene.
Molecular cancer - 13 Jul 2010
Ma Haiqing, Weng Desheng, Chen Yibing, Huang Wei, Pan Ke, Wang Hui, Sun Jiancong, Wang Qijing, Zhou Zhiwei, Wang Huiyun, Xia Jianchuan
Abstract excerpt
BACKGROUND: High frequency of loss of heterozygosity (LOH) was found at D7S486 in primary gastric cancer (GC). And we found a high frequency of LOH region on 7q31 in primary GC from China, and identified D7S486 to be the most frequent LOH locus. This study was aimed to determine what genes were affected by the LOH and served as tumor suppressor genes (TSGs) in this region. Here, a high-throughput single...
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