Article
[Mutations in epigenetic and metabolic regulators in peripheral T-cell lymphoma].
[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Aug 2015
Sakata-Yanagimoto Mamiko
Abstract excerpt
Recent advances in sequencing technologies led us to the discovery of mutations in epigenetic and metabolic regulators in peripheral T-cell lymphoma (PTCL). Frequencies of these mutations were found to be especially high in PTCL with features of follicular helper T cells (TFH). These mutations are also identifiable in myeloid malignancies as well as PTCL, suggesting that abnormalities in epigenetic and metabolic...
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