Article
STK10 missense mutations associated with anti-apoptotic function.
Oncology reports - 1 Oct 2013
Fukumura Kazutaka, Yamashita Yoshihiro, Kawazu Masahito, Sai Eirin, Fujiwara Shin-Ichiro, Nakamura Naoya, Takeuchi Kengo, Ando Mizuo, Miyazono Kohei, Ueno Toshihide, Ozawa Keiya, Mano Hiroyuki
Abstract excerpt
Peripheral T-cell lymphoma (PTCL) is an aggressive lymphoma with a 5-year overall survival rate of <30%. To identify carcinogenesis-related genes in PTCL, we conducted high-throughput resequencing of target-captured cDNA in a PTCL specimen, revealing a total of 19 missense mutations among 18 inde...
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