Article
High resolution SNP array genomic profiling of peripheral T cell lymphomas, not otherwise specified, identifies a subgroup with chromosomal aberrations affecting the REL locus.
British journal of haematology - 1 Feb 2010
Hartmann Sylvia, Gesk Stefan, Scholtysik René, Kreuz Markus, Bug Stefanie, Vater Inga, Döring Claudia, Cogliatti Sergio, Parrens Marie, Merlio Jean-Philippe, Kwiecinska Anna, Porwit Anna, Piccaluga Pier Paolo, Pileri Stefano, Hoefler Gerald, Küppers Ralf, Siebert Reiner, Hansmann Martin-Leo
Abstract excerpt
Little is known about genomic aberrations in peripheral T cell lymphoma, not otherwise specified (PTCL NOS). We studied 47 PTCL NOS by 250k GeneChip single nucleotide polymorphism arrays and detected genomic imbalances in 22 of the cases. Recurrent gains and losses were identified, including gain...
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