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Article

Downregulation of CSN 6 attenuates papillary thyroid carcinoma progression by reducing Wnt/ β ‐catenin signaling and sensitizes cancer cells to FH 535 therapy

17 Jan 2018

Abstract excerpt

The incidence of thyroid cancer has increased worldwide at a rate higher than that of any other cancer. CSN6 is overexpressed in many types of cancers, and such expression is linked to oncogenic activity. However, the detailed biological functions of CSN6 in papillary thyroid cancer (PTC) have not been well characterized. We investigated CSN6 expression in PTC specimens and cell lines. We used short-hairpin...

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PMID: 29341469
DOI: 10.1002/cam4.1272

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