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Article

NOD2/CARD15 mutations and the risk of reoperation in patients with Crohns disease.

Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti - 1 Jun 2015

Martínek L, Kupka T, Simova J, Klvaňa P, Bojková M, Uvírová M, Dítě P, Dvorackova J, Hoch J, Zonca P

Abstract excerpt

INTRODUCTION: Three NOD2/CARD15 gene variants (3020insC, R702W, G908R) have been identified as genetic risk factors for Crohns disease patients. However the diagnostic and therapeutic relevance for clinical practice remains limited. The aim of this study was to evaluate the association between these variants, the risk of reoperation and disease phenotype. METHODS: In 76 Crohns disease patients (41 female, 35...

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Identifiers

PMID: 26174343

Genes

NOD2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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