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Article

Long-Term Follow-Up, Association between CARD15/NOD2 Polymorphisms, and Clinical Disease Behavior in Crohn's Disease Surgical Patients.

Mediators of inflammation - 1 Jan 2021

Giudici Francesco, Cavalli Tiziana, Luceri Cristina, Russo Edda, Zambonin Daniela, Scaringi Stefano, Ficari Ferdinando, Fazi Marilena, Amedei Amedeo, Tonelli Francesco, Malentacchi Cecilia

Abstract excerpt

BACKGROUND: CARD15/NOD2 is the most significant genetic susceptibility in Crohn's disease (CD) even though a relationship between the different polymorphisms and clinical phenotype has not been described yet. The study is aimed at analyzing, in a group of CD patients undergoing surgery, the relationship between CARD15/NOD2 polymorphisms and the clinical CD behavior after a long-term follow-up, in order to...

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Crohn Disease
Gene Frequency
Genetic Predisposition to Disease
Nod2 Signaling Adaptor Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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Identifiers

PMID: 33708009
DOI: 10.1155/2021/8854916
PMCID: PMC7932801

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