Article
NOD2/CARD15 mutations in Croatian patients with Crohn's disease: prevalence and genotype-phenotype relationship.
European journal of gastroenterology & hepatology - 1 Aug 2006
Cukovic-Cavka Silvija, Vermeire Severine, Hrstic Irena, Claessens Greet, Kolacek Sanja, Jakic-Razumovic Jasminka, Krznaric Zeljko, Grubelic Katja, Radic Davor, Misak Zrinjka, Jadresin Oleg, Rutgeerts Paul, Vucelic Boris
Abstract excerpt
BACKGROUND: Crohn's disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract with variations in localization and behaviour. Mutations in the NOD2/CARD15 gene on chromosome 16q have been implicated in the pathogenesis of the disease and three main sequence variants, all single...
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