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Article

Crohn's disease - genetic factors and progress of the disease.

Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia - 1 Jun 2018

Kupka Tomas, Simova Jarmila, Dvorackova Jana, Martinek Lubomir, Motyka Oldrich, Uvirova Magdalena, Dite Petr

Abstract excerpt

BACKGROUND AND OBJECTIVES: Crohn's disease is a multifactorial inflammatory disease affecting mainly the gastrointestinal tract. The genetic factors that are involved in the disease include mainly three mutations of the gene NOD2/CARD15 (R702W, G908R, 3020insC). The aim of this study was to determine the relationship between the presence of these variants and disease phenotype. MATERIAL AND METHODS: 70 patients...

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Source

Identifiers

PMID: 29358789
DOI: 10.5507/bp.2017.058

Genes

NOD2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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