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Article

FYA silencing by the GATA-motif variant FYA(-69C) in a Caucasian family.

Transfusion - 1 Nov 2015

Písačka Martin, Marinov Iuri, Králová Miroslava, Králová Jana, Kořánová Michaela, Bohoněk Miloš, Sood Chhavi, Ochoa-Garay Gorka

Abstract excerpt

BACKGROUND: The c.1-67C variant polymorphism in a GATA motif of the FY promoter is known to result in erythroid-specific FY silencing, that is, in Fy(a-) and Fy(b-) phenotypes. A Caucasian donor presented with the very rare Fy(a-b-) phenotype and was further investigated. STUDY DESIGN AND METHODS: Genomic DNA was analyzed by sequencing to identify the cause of the Fy(a-b-) phenotype. Samples were collected from...

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PMID: 26173389
DOI: 10.1111/trf.13221

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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