Article
First example of an FY*01 allele associated with weakened expression of Fya on red blood cells.
Immunohematology - 1 Jan 2015
Arndt Patricia A, Horn Trina, Keller Jessica A, Heri Suzanne M, Keller Margaret A
Abstract excerpt
Duffy antigens are important in immunohematology. the reference allele for the Duffy gene (FY) is FY*02, which encodes Fy(b). An A>G single nucleotide polymorphism (SNP) at coding nucleotide (c.) 125 in exon 2 defines the FY*01 allele, which encodes the antithetical Fy(a). A C>T SNP at c.265 in the FY*02 allele is associated with weakening of Fy(b) expression on red blood cells (R BCs) (called Fy(x)). until...
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