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Article

KRAS mutation status is associated with specific pattern of genes expression in pancreatic adenocarcinoma.

Future oncology (London, England) - 1 Jan 2015

Bittoni Alessandro, Piva Francesco, Santoni Matteo, Andrikou Kalliopi, Conti Alessandro, Loretelli Cristian, Mandolesi Alessandra, Lanese Andrea, Pellei Chiara, Scarpelli Marina, Principato Giovanni, Cascinu Stefano

Abstract excerpt

AIMS: To evaluate potential differences at a molecular level between KRAS mutant tumors (MT) and KRAS wild-type (WT) pancreatic tumors and the biological and prognostic significance of different KRAS mutations. MATERIALS & METHODS: Expression of a panel of 29 genes was analyzed in KRAS WT and MT tumors. Effects of KRAS mutation and gene expression levels were assessed on patients' survival. RESULTS: MUC6 (p =...

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Source

Identifiers

PMID: 26161927
DOI: 10.2217/fon.15.98

Genes

KRAS
HGF
IHH
SHH
SMAD4
VEGFB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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