Article

Elevated KRAS protein level is associated with better survival in pancreatic cancer

2025-05-13

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Activating somatic <italic>KRAS</italic> mutations in hotspot loci occur almost universally (> 95%) in pancreatic ductal adenocarcinoma (PDAC). Both the presence of a <italic>KRAS</italic> mutation and high mRNA expression levels of <italic>KRAS</italic> in tumor tissue have been associated with worse outcome. Less is known about the expression of KRAS at the pro...

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Literature Corpus work: 680b1c31-06d4-57c1-91d6-0fe7b6ba8e52
DOI: 10.21203/rs.3.rs-6542241/v1

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