Article
A special subtype: Revealing the potential intervention and great value of KRAS wildtype pancreatic cancer.
Biochimica et biophysica acta. Reviews on cancer - 1 Jul 2022
Xu Zhi-Hang, Wang Wen-Quan, Liu Liang, Lou Wen-Hui
Abstract excerpt
Pancreatic ductal adenocarcinoma (PDAC) is the predominant form of pancreatic cancer and has devastating consequences on affected families and society. Its dismal prognosis is attributed to poor specificity of symptoms during early stages. It is widely believed that PDAC patients with the wildtype (WT) KRAS gene benefit more from currently available treatments than those with KRAS mutations. The oncogenic genetic...
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