Article
KRAS in pancreatic cancer.
JOP : Journal of the pancreas - 28 Jul 2014
Agarwal Archana, Saif Muhammad Wasif
Abstract excerpt
Pancreatic cancer is one of the most feared malignancies. The most common form of pancreatic cancer is adenocarcinoma arising from the ductal epithelium. KRAS is the most common oncogene that has been found to be mutated. However, targeting KRAS directly has been difficult. We do not know a lot about the relationship between KRAS and other signaling pathways. At the same time, little is known about the non KRAS...
Topics
- Adenocarcinoma
- Ascitic Fluid
- Gene Expression Regulation, Neoplastic
- Humans
- Mutation
- Pancreatic Neoplasms
- Prognosis
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins p21(ras)
- Signal Transduction
- Survival Analysis
- ras Proteins
