Article
The KRAS signaling pathway's impact on the characteristics of pancreatic cancer cells.
Pathology, research and practice - 1 Aug 2023
Chen ZhangXing, Chen Meiyan, Fu Yuka, Zhang Jingyi
Abstract excerpt
Pancreatic ductal adenocarcinoma (PDAC) is classified as a cancer with high metastasis so that its mortality rate is high and most of the patients could not survive longer than 5 years. RAS signaling participate in cellular processes, so it has a key role in PDAC.RAS activation is associated via three different signaling pathway including somatic oncogenic point mutations in KRAS, upstream signaling like EGFR,...
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