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Article

SNP interactions of Helicobacter pylori-related host genes PGC, PTPN11, IL1B, and TLR4 in susceptibility to gastric carcinogenesis.

Oncotarget - 7 Aug 2015

He Caiyun, Tu Huakang, Sun Liping, Xu Qian, Gong Yuehua, Jing Jingjing, Dong Nannan, Yuan Yuan

Abstract excerpt

A series of host genes that respond to Helicobacter pylori (H. pylori) infection are involved in the process of gastric carcinogenesis. This study sought to examine interactions among polymorphisms of H. pylori-related genes PGC, PTPN11, TLR4, and IL1B and assess whether their interaction effects were modified by H. pylori infection. Thirteen polymorphisms of the aforementioned genes were genotyped by the...

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Topics

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Share to Carcinogenesis
Share to Epistasis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gastritis, Atrophic

Share to Helicobacter Infections

Share to Helicobacter pylori

Share to Interleukin-1beta

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 11

Share to Toll-Like Receptor 4

Source

Open in PubMed Open full text

Identifiers

PMID: 26158864
DOI: 10.18632/oncotarget.4231
PMCID: PMC4662472

Genes

PGC
PTPN11
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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