Article
Association of genetic polymorphisms of interleukins with gastric cancer and precancerous gastric lesions in a high-risk Chinese population.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Feb 2016
Wang Yu-Mei, Li Zhe-Xuan, Tang Fu-Bing, Zhang Yang, Zhou Tong, Zhang Lian, Ma Jun-Ling, You Wei-Cheng, Pan Kai-Feng
Abstract excerpt
Helicobacter pylori (H. pylori) infection and cytokine-mediated inflammatory responses play important roles in gastric cancer (GC) pathogenesis. To investigate an association between genetic polymorphisms in interleukin (IL)-1β, IL-4R, IL-8, IL-10, IL-16, IL-18RAP, IL-22, and IL-32 and risks of GC and its precursors, a population-based study was conducted in Linqu County. Genotypes were determined by Sequenom...
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