Article
Helicobacter pylori-related host gene polymorphisms associated with susceptibility of gastric carcinogenesis: a two-stage case-control study in Chinese.
Carcinogenesis - 1 Jul 2013
He Caiyun, Tu Huakang, Sun Liping, Xu Qian, Li Ping, Gong Yuehua, Dong Nannan, Yuan Yuan
Abstract excerpt
Stomach carcinogenesis progresses stepwise from normal mucosa/superficial gastritis, atrophic gastritis (GA) to gastric cancer (GC). Host factors independent of or combined with Helicobacter pylori infection may modulate the carcinogenesis process. In this two-stage study, we selected 24 putative functional tag single-nucleotide polymorphisms (tagSNPs) for six H.pylori-related host genes, MUC1, toll-like receptor...
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